Sentence examples for modulation of mechanisms from inspiring English sources

The modulation of mechanisms affecting the fate of CsA at absorption site (P-gp and CYP3A4 in intestine) may be the reason of reduced absorption.

Traditionally, cancer cells that survive chemotherapy and acquire drug resistance are thought to give rise to a population of drug-resistant cancer cells through modulation of mechanisms such as drug inactivation, changes in the expression of cellular targets, suppression of drug accumulation, and inhibition of drug activation [ 130– 132].

Because cell death mechanisms play a role in OA pathogenesis, modulation of these mechanisms may have substantial therapeutic potential.

Moreover, modulation of such mechanisms by migraine prophylaxis has been shown in the visual and motor cortex [43 45].

Despite the overwhelming data suggesting that cranial parasympathetic activation may be important in the modulation of trigeminovascular mechanisms related to headache, one study suggests the contrary.

Modulation of adrenergic mechanisms by GFC may serve as an effective countermeasure in amelioration of prefrontal deficits and neurodegenerative changes during HH.

In this model, learning under AP5 leads to a change in the contextual gain on the learned association, possibly via the modulation of attentional mechanisms.

Ca2+ signal transduction is involved in the detection of energy or oxygen deficits and the modulation of downstream mechanisms to promote anaerobic germination in rice (Lee et al. 2009).

From these findings, it can be speculated that the potential role of miRNAs in the modulation of transcription mechanisms would mostly consist in a fine-tuning process rather than striking regulations.

Therefore, sphingolipids contribute to the modulation of the mechanisms of cancer initiation and progression and the sensitivity to anti-tumor treatments.

Modulation of TIGAR‐related mechanisms may therefore be a promising novel strategy to develop disease‐modifying therapy for PINK1‐related PD.