Sentence examples for modulation of hypoxia from inspiring English sources
The present study was designed to assess the role of neferine in modulation of hypoxia induced autophagy in muscle cells.
Also the modulation of hypoxia from targeting tumour vasculature is another area of clinical interest that can profit from such measurements.
Most recently, linc-ROR has been reported to be involved in modulation of hypoxia signaling pathways in hepatocellular carcinoma (HCC) cells.
Conversely, modulation of hypoxia may provide benefit to patients with HNSCC [ 18], which underscores the importance of understanding the impact of therapies on tumor hypoxia and developing improved methods to modulate tumor pO2 and the molecular response to hypoxia.
The induction of putative proapoptotic, cell cycle arrest pathways commonly occurs (IGFBP-3 and CCNG2) and may act to select apoptosis resistance pathways in vivo, and therefore a more comprehensive analysis in clinical trials may help refine predictions of those who would benefit from modulation of hypoxia and the variability in outcome even when using GLUT1.
In the present study we tested the hypothesis that EA prevents inflammatory response and weight gain in obese mice through modulation of hypoxia-inducible factors-1α (HIF1-α -dependent patHIF1-α -dependentipose tissues.
An understanding of the biology of the HIF transcription family may eventually lead to the development of therapies that are aimed at interfering with this key signalling pathway, and hence to modulation of hypoxia-dependent pathologies such as RA.
MG was recently reported to play a physiological role in the modulation of hypoxia-induced-factor-1α (HIF-1alpha) levels and thus in the modulation of the balance between anaerobic and aerobic bioenergetics [ 12].
The present study aimed at investigating the potential anti-angiogenic effect of AST in colon cancer, by examining the modulation of hypoxia-inducible HIF-1α and VEGF and the involving signaling pathways.
It has previously been reported that hypoxia can have varied effects across different kinase inhibitors, and this may be partially mediated by modulation of hypoxia-induced compensatory mechanisms, such as VEGF signalling [ 76].
Based on the assumption that there are genes that are regulated by HIF-1α, HIF-2α or both, an understanding of the biology of the HIF transcription family may eventually lead to the development of therapies aimed at interfering with this key signalling pathway, and hence to modulation of hypoxia-dependent pathologies such as RA.
