Sentence examples for modulation of histone from inspiring English sources

Zhou, Q. et al. TGFbeta mediated transition of corneal fibroblasts from a proinflammatory state to a profibrotic state through modulation of histone acetylation.

Jumonji C domain-containing proteins were first identified with a role in the modulation of histone methylation marks.

The dynamic modulation of histone acetylation in plants is shown to be important for plants to adapt their growth and development to environment changes such as light, temperature, biotic, and abiotic stresses (Chen and Tian 2007; Servet et al. 2010).

One of the major epigenetic regulations is modulation of histone acetylation levels at genes required for certain biological processes.

The angiotensin type 1 receptor (AT1R) is an ideal model system for exploring modulation of histone imprints by a GPCR.

In addition to S1P's extracellular action, there is evidence that supports an intracellular role of S1P in calcium release [13], [14] and modulation of histone acetylation via HDACs in breast cancer cells [15].

Modulation of histones by GPCR is most likely a cis-acting epigenetic chromatin regulatory mechanism.

Numerous studies suggested that chromate induced DNA damage, mutation, genetic instability and epigenetic modulation of histones and DNA may contribute to its carcinogenicity, however, the molecular mechanisms of Cr VI) induced lung cancer are not well understood.

Further, the modulations of histone methylation and acetylation by chrysin might initiate several levels of chromatin modification in the multiple sites such as −684 to −692, −2549 to −2557 required for transcriptional regulation of p21 gene [ 51].

Although the NAP-family proteins are well-characterized core histone chaperones, recent findings reveal that both NAP1 (hNand) and SET also interact with linker histone H1, and have been linked to chromatin decondensation through modulation of linker histone H1 dynamics [ 43– 43].

Here we show that NF-Y exerts its effect on transcription through the modulation of the histone "code".