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Orexin inhibits responses to CCK suggesting a role in modulation of gut to brain signaling.
Zhang, X. et al. Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats.
The results suggest that modulation of gut microbial composition from probiotic consumption may contribute to altered energy metabolism and body composition.
Polysaccharide is efficient in attenuation of metabolic ailments and modulation of gut microbiota as prebiotics.
Thus, modulation of gut microbiota (by probiotics or other dietary intervention) or direct targeting of gut microbiota enzymes (by pharmacological inhibitors or activators) may be a growing area for pharmaceutical and functional food industries, with the goal of decreasing the widespread growth of adiposity, insulin resistance, AD, and other metabolic diseases.
While the causal relationship to atherosclerosis inhibition is not known, these crude profiles of the predominant endogenous gut bacteria indicate that further studies with more thorough methodology are warranted to investigate whether the beneficial effects of VSL#3 were mediated via compositional modulation of gut microbiota.
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Beside an increased energy harvest from the diet, further mechanisms linking gut microbiota to obesity have been subsequently proposed, including chronic low-grade endotoxinemia, regulation of tissutal biologically active fatty acid composition and modulation of gut-derived peptide secretion.
This review has tried to summarize the current knowledge in relation to the phenolic metabolism by gut microbiota and the modulation of the gut microbiota by phenolic compounds and polyphenol-rich dietary sources.
Furthermore, obese humans have reduced gut microbial diversity, 7 and modulation of the gut microbiota either by antibiotics or prebiotics improves metabolic and inflammatory properties, suggesting a direct role of the gut microbiota in metabolic diseases.
Reducing endotoxin leakage from the gut into the bloodstream, perhaps by modulation of the gut microbiota, was suggested as a target in the strategy to reduce metabolic disease.
Changes in gut microbiota, VOCs, and LPS will elucidate the effects of prebiotic modulation of the gut microbiota and their metabolic by-products.
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manipulation of gut
modification of gut
diversity of gut
modulation of pHi
modulation of movement
modulation of cholesterol
modulation of virus host
modulation of attention
modulation of scFv
modulation of receptor
modulation of brain
modulation of pain
modulation of inflammation
modulation of calcineurin
modulation of activity
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