Sentence examples for modulation of glucose from inspiring English sources

The direct modulation of glucose uptake is suggested by the suppression of AS160 phosphorylation, which regulates Gluts trafficking, localisation or recycling.

GPR119 receptor has been proposed as a metabolic regulator playing a pivotal role in the modulation of glucose homeostasis in type 2 diabetes.

Conversely, in models of MET amplification, the 18F-FDG uptake does not reliably reflect this type of resistance since modulation of glucose consumption and proliferation appear to be uncoupled.

18F-FDG PET demonstrated tumour-specific modulation of glucose uptake only following AZD8186 administration with no differences seen in peripheral tissues making it a very effective combination partner for use with other PI3K inhibitors and confirming the differentiating factor of PI3Kβ inhibitors as a whole.

However, we cannot rule out alternative physiological mechanisms that link TAS2R function to the modulation of glucose homeostasis.

By combining human genetic approaches with high-throughput receptor screening, we have identified an important link between taste receptor function and the modulation of glucose homeostasis.

The kidneys play an important role in the modulation of systemic glucose levels, filtering and reabsorbing glucose back into the circulatory system.

Reducing exogenous insulin doses, coupled with modulation of the glucose content of nutrition would diminish the impact of sudden changes of insulin sensitivity on glycaemic outcome.

This study reported an improvement in the vascular function through modulation of the glucose levels and inflammation and oxidative stress biomarkers after the consumption of the commercial whey derived peptide NOP-47 by healthy individuals [ 57].

Thus it plays a key role in the transduction of regulatory and proliferative signals arising out at the cell membrane in the insulin signalling pathway, leading to potential modulation of blood glucose levels [ 17].

Since Puerto Rico has the highest rate of Type 2 diabetes within all the states and territories of the United States, and Puerto Ricans commonly use plants as diabetes adjuvants, it is important to study the plants' physiological effects, and identify their bioactive compounds to understand their role in modulation of blood glucose levels.