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& Dai, X. Decadal modulation of global surface temperature by internal climate variability.
However, TSA is known for many non-target effects [41], including modulation of global gene expression.
The H2A isoforms and PTM could directly affect chromatin structure and function of chromatin which is critical for the modulation of global gene expression.
Modulation of global protein synthesis, degradation, or both, can lead to either cellular hypertrophy or atrophy.
Our theoretical results show that the modulation of global flux variability requires that growth rate is regulated in response to changes in environmental conditions.
Consequently, long-term modulation of global DNA methylation, which also acts at exon 2 of POLGA, induces differentiation by synchronously reducing multipotent gene expression while increasing mtDNA copy number and endpoint gene expression.
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The enzymes have more likely evolved to allow fast adaptation of bacterial cells to changing environments by modulation of the global rate of translation, and the term "toxin" is therefore misleading.
A soybean 70-mer oligo array containing 19,200 features was used to study the modulation of the global transcript profile of soybean cotyledons at 6 different time points relative to the imbibed seed.
The nature (turn on/off or modulation) of a global regulation in a metabolic pathway allows to build hypotheses on its physiological role, and to make predictions on the involvement of the pathway in the general organization of the metabolic function.
We predicted that this might correlate to modulation of activity of "global neuronal workspace" neurons and co-activated local processors in visual or auditory regions.
These data highlight the interactive nature of the processes and cofactors in the modulation of VILI-like global and/or regional pulmonary hemodynamics; the presence, type, and timing of secondary lung insults; and interactions between regional heterogeneity of pulmonary perfusion and regionally heterogeneous peak airspace strains.
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