Sentence examples for modulation of existing from inspiring English sources

Synthetic biology encompasses the design of new biological parts and systems as well as the modulation of existing biological networks to generate novel functions.

For paralogous protein superfamilies, such as the GPCR superfamily undertaken in our study, the germ of the function of novel proteins is usually present in its ancestor(s), and new proteins with novel functions arise mainly by the modulation of existing ones.

Whether expansion of the distal Hoxd domain at the fin-to-limb transition was accomplished by modulation of existing regulatory elements, evolution of new enhancer sequences, or by sustained production of mitogenic factors, such as Fgfs from the apical ridge, is unknown.

Interestingly, despite the differences among mutualistic symbioses in nature, the molecular modulation of existing pathways in the host cell seems to be a key common factor in symbiosis regulation [ 21- 23].

The resulting horticultural plant, devoid of DNA from other gene pool and restricted to a modulation of existing traits from the sexually compatible gene pool, could also result in less comprehensive regulation towards the release of a precision bred plant, thereby decreasing the regulatory approval costs.

Furthermore, the BER performance of the proposed modulation scheme is compared with the performance of existing modulation schemes.

Broadly, this encompasses treatments requiring the strong induction of immune responses, both humoral and cell mediated, or the down modulation of an existing pathological immune response, either through immune deviation or suppression.

The success of heterologous boost vaccines may depend on the modulation of the existing mycobacteria-specific T-cell repertoire to possess more "favorable" functional characteristics, rather than inducing de novo T-cell responses.

To determine whether TGF-β-induced EMT requires de novo transcription and translation and cannot be established exclusively by signaling-mediated modulation of the existing proteome, we treated NMuMG cells with inhibitors of transcription or translation shortly before exposure to TGF-β and observed that EMT was completely blocked under these conditions (Supplementary Fig S1B).

We wondered whether or not increased synaptic activity, seen in response to ketamine injection, might be due to an increase in the number of individual excitatory synapses or modulation of the strength of existing synapses.

The performance of this scheme is compared with that of existing PSM and its combined modulation schemes by using two sets of orthogonal pulses.