Sentence examples for modulation of diverse from inspiring English sources

TLR stimulation by various agonists was shown to activate Notch signaling resulting in modulation of diverse target genes involved in pro-inflammatory responses in macrophages [13], [36] [37].

Along with the conventional role of the nucleolus in ribosome biogenesis, additional roles in the modulation of diverse molecular pathways have been described recently [13], [14].

The second important finding is that peripherally administered UAG has activity in the absence of the GHSR, as indicated in pathways analyses by the modulation of diverse signaling pathways including [Ca2+]i, cAMP, "growth factors", Notch and Wnt.

Vitamin A is an essential micronutrient that regulates many biological processes through modulation of retinoic acid receptor-responsive genes, acting as a systemic antioxidant and participating in the modulation of diverse redox mechanisms involved in physiological and pathological processes.

Once activated, the catalytic domain of mTOR phosphorylates substrates associated with raptor, which functions as a crucial scaffold placing bound substrates in close proximity to mTOR and enabling modulation of diverse downstream processes.

Akt is involved in activation/phosphorylation of numerous downstream targets implicated in the modulation of diverse pathways governing cell survival decisions, including those associated with glycogen synthase kinase (GSK), m-TOR/p70rsk, and NF- κB, among others.

Identification of the molecular mechanisms of autophagy modulation under diverse conditions is critical for the development of therapeutic drugs.

Recent advances in the design of synthetic RNA switches capable of detecting and responding to molecular and environmental signals enable dynamic modulation of gene expression through diverse mechanisms, including transcription, splicing, stability, RNA interference, and translation.

Thus, whether differential modulation of Dicer activity in diverse cell types and/or physiological conditions is underlying the relative abundance of 5'-trimming miR-101 isomiRs is an open question that deserves specific research.

Apart from their function in the Rhizobium-legume and in different plant-soil pathogen interactions, flavonoids have been implicated in the modulation of developmental processes as diverse as auxin transport, pollen germination, root hair growth, allelopathic responses and in systemic acquired resistance [ 31].

The modulation of cytokine levels in meningitis of diverse bacterial etiologies may be a useful strategy to improve the outcome in terms of morbidity and mortality.