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Tuberculosis clinical severity is multi-factorial and cytokines play a pivotal role in the modulation of disease severity.
The model has provided examples of modifying loci (called modifiers of Min, Mom) in mice, demonstrating the principle of genetic modulation of disease severity represented by, in these cases, intestinal adenoma multiplicity.
MIF was shown to be involved in inflammatory atherosclerosis pathogenesis and is implicated in modulation of disease progression [ 7, 8].
The modulation of disease severity is partly thought to be through a complex, dose-dependent influence on cytokine production [ 6].
In animal populations, susceptibility to virus infection and the modulation of disease progression display inter-individual variability [ 7– 9].
For the Transregional Collaborative Research Centre "Organ Fibrosis: From Mechanisms of Injury to Modulation of Disease" (SFB/TRR57).
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The mechanisms underlying our findings are not well understood, but improvement in temperature sensation appears to be a sign of modulation of disease-related brain network abnormalities.
Nevertheless, as described in this review, pharmacological modulation of disease-associated miRNAs has demonstrated promising therapeutic potential and appears to be well tolerated based on data from short-term studies in animal disease models and human patients.
Therefore, direct measurements are critical to better understand the progress and modulation of diseases, such as osteoarthritis, as well as to enhance the design, surgical implantation and postoperative care of the reconstructed knee.
These compounds can be applied in the treatment of T-cell-mediated auto-immune disease for specific modulation of the disease process.
The distinct modulation of the disease activity index and histological damage was also confirmed by a significant reduction of MPO activity in the colonic mucosa of Gal-4 treated mice compared to control animals (p < 0.05) and increased colon length (not shown).
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modulation of virus
modulation of disorder
modulation of diseases
modulation of sunspot
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modulation of activity
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modulation of cholesterol
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modulation of attention
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