Sentence examples for modulation of collagen from inspiring English sources
Thus, prolonged exposure to ET-743 may cause changes in cell function through cytoskeleton rearrangement and/or modulation of collagen levels.
Because of these findings, periostin is recognized as an important player in the modulation of collagen fibrillogenesis and integrin signaling.
The data implicate DDR2 in modulation of collagen processing and tensile wound strength during tissue healing.
YKL-40 protein is involved in proliferation of fibroblasts and modulation of collagen formation, facilitating tumor invasion, and metastasis [ 13].
The nanobiocomposite promote wound healing by modulation of collagen deposition and regulation of keratinocytes and support the essential re-epithelialization process.
One hypothesis for the role of decorin in mineralization is that its modulation of collagen fibrillogenesis in the extracellular matrix indirectly affects hydroxyapatite crystal growth [ 59].
These data demonstrate a role for IL-21 in the modulation of collagen-specific T-cell responses and the pathology of arthritis, supporting a rationale for blockade of the IL-21 pathway in rheumatoid arthritis.
Indeed, previous findings on both dermal fibroblasts showing a potent induction of MMP-1 [ 18] and on articular chondrocytes that show minimal modulation of total collagen synthesis by relaxin [ 31] lend credence to this hypothesis.
This study investigated the modulation of type I collagen gene expression in normal fibroblasts by breast tumour cells.
It was interesting that cells isolated from the outer meniscus were relatively more responsive to 5% oxygen tension than were inner meniscus cells, based on the large modulation in gene expression of collagen types I and II, SOX9 and P4Hα(I).
As shown in Figure 3A, NHLF migration through collagen I-coated inserts was significantly inhibited in the presence of DDR2-specific, but not DDR1-specific, siRNA, suggesting a role for DDR2 in the modulation of fibroblast migration though collagen I.
