Sentence examples for modulation might represent from inspiring English sources

Thus, CB2R modulation might represent a promising therapeutic target that lacks psychotropic effects and can be used to exploit ECS-based approaches to counteract neuronal degeneration.

Our results prove the twofold role of P2X7 in the course of ALS and establish that P2X7 modulation might represent a promising therapeutic strategy by interfering with the neuroinflammatory component of the disease.

In fact, these agents have been shown to modulate the activity of proteins involved in autophagic process, leading to the concept that its modulation might represent a valuable therapeutic target in patients affected by several malignancies, including prostate cancer [ 11, 12].

Present study suggests that nitric oxide modulation might be involved in the protective effects of venlafaxine.

When pain becomes chronic tDCS modulation might be less prominent[14].

This modulation might be expressed as an up-regulation on their survival [ 24].

Modulation of this pathway might represent a potential target for treatment for septic and ARDS patients.

This suggests that the expression levels and signalling competence of Gab2 needs to be tightly controlled in Bcr-Abl+ CML in order to drive proliferation and to repress differentiation at the same time, raising the possibility that modulation of Gab2 signalling might represent a strategy to control this disease.

In addition, impairment of antitumoral T cell responses and modulation of immune responses by immune complexes might represent underlying mechanisms that also promote tumor progression [ 52].

Since the ability of syndecan-1 to bind growth factors and initiate signaling is dependent on the amount, position, and the orientation of the sulfate groups on the HS chains [ 29– 34], the modulation of these enzymes by syndecan-1 might represent an important feedback mechanism.

If true, modulation of Bcl-xL expression level and/or activity might represent an interesting strategy to optimize the efficacy of chemotherapeutic agents in this particular tissue, as liver cancer represents a significant source of morbidity and mortality worldwide [ 38].