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Therefore, the genes affected by EZH2 modulation may differ in luminal and basal cancers.
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Interestingly, control of SOX2 expression and its modulation of apoptosis may differ in EGFR-mutant lung cancer, compared with other forms of NSCLC.
There has been some suggestion that rapamycin-mediated modulation of different markers of glucose metabolism may differ depending on the time course of treatment, though this may be dependent on the model used and method of treatment.
Because the nature of spinal reflex modulations during passive and active conditions may differ (Racinais et al. 2013), H-reflex and V-wave responses were assessed during voluntary efforts/background contractions.
Thus, acupuncture analgesia may differ from classical conditioned pain modulation [ 14].
Although the extent of modulation revealed by real-time RT-PCR and RNA-Seq may differ [ 6, 48, 49], the real-time RT-PCR expression profiles in our analysis were in complete agreement with the RNA-Seq data for 19 genes.
Accordingly, a review by Suwa et al. states that SHIP2 shows both prooncogenic effects and anticancer effects for SHIP2 function may differ based on interactive and imbalanced modulation by upstream stimulators including insulin, EGF, and IGF-I and downstream molecules including Akt2, tyrosine kinase receptor, and focal adhesion adaptor proteins [ 26].
Genetic modulation of MDM2 levels in mice also suggests that p53 regulation during homeostasis may differ from its regulation in cancer tissues (O'Leary et al, 2004).
These findings could relate to a modulation of VacA activity on host cells in the Thai isolate-VacA toxin that may differ from those of the model strain.
Each PHY standard provides various channel modulation rate (e.g., 1, 2, 5.5, 11 Mbps for 802.11b and 6, 12, 24 Mbps for 802.11a); thus the performance may differ in accordance with AP configuration setting.
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