Sentence examples for modulation is mediated from inspiring English sources

Based on these results, the current study was designed to test the hypothesis that both exogenous and endogenous cannabinoids can selectively modulate glutamatergic afferents to CA3 pyramidal cells, and that such modulation is mediated by cannabinoid type 1 (CB1) receptors.

This modulation is mediated by a complex system of neurochemical and electrical on-off switches.

Whether this modulation is mediated through physical or functional interactions only remains to be determined, but it is clear that the relevant interactions do not involve a positive regulation, as is the case for EcSSB, T7 gp2.5 and T4 gp32, and their respective DNA polymerase partners at the replication fork.

This modulation is mediated by the classical MAP kinase cascades via Erk1/2 [ 99].

Our data strongly imply that this modulation is mediated by a direct VGCC-Munc13 interaction although we cannot exclude that synprint interaction site on Munc13 C2B influences interactions with other proteins in situ that in turn modulate VGCCs.

Thus, the double knockdown cells allow us to test whether the growth inhibitory effect of β-TrCP modulation is mediated via AhR upregulation.

Our results also demonstrate that JNK kinase Hep is involved in regulating the expression of SMGs and show that infection effects on SMG modulation are mediated locally at the site of injury and infection but not systemically.

B cell modulation was mediated by soluble factors (e.g. IL-6) secreted by MSC when PBMC were used as responder cells [ 130].

We showed that a significant part of this modulation was mediated by BAP triggering NMDA nonlinearities as well as BAC firing (Larkum et al. 1999; Stuart and Hausser 2001) due to coincidence of the spike induced by the thalamic input and the intracortical (dendritic) input arising from the local cortical microcircuit of cells with similar stimulus preference.

Rac1 modulation of NFκB is mediated by ROS, and leads to the expression of inflammatory mediators: IL1 and collagenase-1, member of the MMPs (matrix metalloproteinases). [ 38] ROS are known to trigger inflammasome activation, resulting in caspase-1-mediated activation and release of IL1β [ 39].

The Wnt modulation by Wise is mediated by its binding to the extracellular domain of Lrp6.