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Epigenetic modulations are supposed to participate in etiology of migraine, but few clinical evidence suggest that DNA methylation modulation is involved in migraine [9].
Third, because of obvious difficulties in obtaining the specific tissue derived from trigeminovascular or cerebral biopsies, we cannot provide direct evidence that epigenetic modulation is involved in migraine.
The present study suggests that nitric oxide modulation is involved in the protective effect of Curcumin in ameliorating sleep deprivation-induced behavioral alterations and oxidative damage.
In episodic tension-type headache, referred pain from the pericranial musculoskeletal tissue and stress probably play an important role, while an altered central pain modulation is involved in the chronic form.
In the hippocampus, heterosynaptic modulation is involved in Long-Term Potentiation (LTP) and consolidation of long-term memory.
We finally mapped the revealed co-expression and expression patterns onto the core network of the cell cycle to further examine how the transcriptional modulation is involved in the core activities of the cell cycle in ESCs.
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In addition, our research also revealed that hypermethylation (an epigenetic modification event in mammals) of the WTH3 promoter and transcription factor modulation were involved in its differential expression in MCF7/AdrR vs MCF7/WT cells (Tian et al, 2005b).
Our research revealed that hypermethylation (an epigenetic modification event in mammals, which represses gene expression) [ 17- 22] of the WTH3 promoter and transcription factor modulation were involved in its differential expression in MCF7/AdrR versus MCF7/WT cells [ 15].
Possibly, different neuroanatomical and neurochemical modulations are involved in the left and right prefrontal neural networks to explain such differences in cognition and behavior.
CB2R-related modulation of leukocyte activation is involved in the impaired immune response following CNS injury.
Rosiglitazone did attenuate the MPP+-induced reduction in GST activity suggesting that modulation of GST activity is involved in the early anti-oxidant effects of rosiglitazone.
More suggestions(15)
modulation is proposed
modulation is found
modulation is implemented
modulation is adopted
modulation is provided
modulation is deployed
modulation is exerted
modulation is expected
modulation is known
modulation is investigated
modulation is assumed
modulation is carried
modulation is used
modulation is identified
modulation is demonstrated
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