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We have previously talked about the second-order cyclic features for communication signals, and we saw that the carrier frequency features tend to vanish from the SCD plane if the modulation is complex.
The nature of this modulation is complex, particularly on climate time-scales (decades or longer).
The mechanism of pain modulation is complex and many studies have either failed to show any associations between COMT variation and pain sensitivity [ 45, 46], while other studies have found an association with pain sensitivity and variation in dosage requirement of morphine in cancer pain patients [ 25].
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The proposed mechanisms of action of nicotinic acid with regards to lipid modulation are complex.
156 As additional information is acquired about ROS and their role in adaptive immune activation, we are beginning to realize that immune modulation by ROS is complex, due in part to their dependence on localized concentration and environment.
The mechanism of CaM/Ca2+ modulation of CNG channels is complex and depends on their composition.
The role of leptin in the modulation of insulin sensitivity is complex.
What's worse, when the background is complex, with modulation levels distributed for a large range, it is difficult to segment the background by just modulation.
The COMT effect is complex, with modulation by both levodopa therapy and task demands (Williams-Gray et al., 2007 b, 2009 a ).
The role of oncogene modulation in response to AT1R blockers is complex, with some oncogenes being inhibited [ 30, 31], while some being up-regulated [ 32].
The mechanism of action of IFN α in CML is complex, including direct modulation of gene expression in LSCs, induction of apoptosis, anti-proliferative signals and immunomodulatory effects.
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