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Although this flight took place near solar maximum, calculations of the broadening effects of solar modulation indicate that a narrow feature of sufficient intensity should still be observable.
The tumour response and target biomarker modulation indicate that the combination is clinically and biologically active.
Differences in the cytokine modulation indicate that at least a part of the IL-6 production could be directed and not mediated by TNF- α activation [ 50].
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All of the evaluated studies were successful in identifying at least one bioactive compound causing angiogenesis modulation, indicating that the identification of highly specific endpoints on the organism level might be a good requirement for the efficient use of zebrafish bioassays in EDA.
Cell lines with high TfR expression significantly correlated with high degrees of modulation indicating that high TfR expressing tumor cells would be more efficiently inhibited by this combination treatment than low TfR expressing ones.
Most of the large saccadic spikes occurred in the direction of and near the peaks and troughs of the smooth modulation, indicating that these saccades were in the forward direction of the target motion.
However, transwell experiments demonstrated that direct contact between CD8+ T cells and MICA-expressing tumor cells caused NKG2D down-modulation, indicating that surface MICA was responsible for that defect [ 57].
In conclusion, the novel finding of the present study that peripheral dopamine may be involved in peripheral pain modulation means (indicates) that peripheral dopamine could be implicated in the pathophysiology of M-TMD and other chronic pain conditions.
The neuronal activity levels reduced to control baselines (relative LFP powers are close to 1) during optogenetic modulation, which indicates that activating the DGH inhibitory neurons is sufficient to rescue ongoing behavioral seizures.
We were not able to achieve stable modelocking with a still lower modulation depth, indicating that it may be difficult to produce slightly longer pulses using this method.
These results indicate that modulation of the population of FEF neurons during eye-pursuit was significantly correlated with modulation during gaze-pursuit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com