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To date, NGE does not appear to have a biological function, whereas NEI has been implicated in dopamine system modulation in several brain regions [45].
In addition, PIMT/TGS1 is pivotal for transcriptional modulation in several contexts.
Although these changes must involve modulation in several protein properties, recent work has mostly emphasized the role of protein stability in molecular evolution [ 3– 6].
Although evidence on health effects in humans is debatable, endocrine modulation in several animal species has been reported following exposure to high levels of isoflavones from soy and red clover (Bennetts et al., 1946; Setchell et al., 1987; Adams, 1995).
Expression of slc11a2-α and slc11a2-β was also evaluated 4 days after iron modulation in several sections of the digestive tract, in order to identify the portion of the intestine responsible for the response of slc11a2-α.
Rsv exerts its cytotoxic and cytostatic effects through specific cell cycle modulation in several cancer types, including S-phase arrest in ovarian cancer [ 25] and medulloblastoma cells [ 26], G1 arrest in prostate cancer [ 27] and melanoma [ 28] and S/G2 arrest in leukemia cells [ 29].
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Also, the BI and BII conformational sub-states of phosphate groups appear associated with minor groove modulations in several DNA-protein complexes [8], [11], [13], [14].
To distinguish between speech and music, Scheirer and Slaney [44] determine the modulation in addition to several other features.
The analysis of heart rate variability (HRV) has been shown as a promising noninvasive technique for assessing the cardiac autonomic modulation in trauma, and several recent studies have demonstrated an association between HRV and clinical outcome [2].
It is well-documented that dehydroepiandrosterone (DHEA) exhibits various behavioral effects in rodents, at least one of which is modulation of learning/memory processes in several test paradigms.
The scale-free behavior exhibited by mitochondrial network dynamics would allow modulation of intracellular timekeeping in several time scales simultaneously.
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