These observations, though indirectly, might lend support the idea that BDNF influence on MOH is played in terms of impulsivity modulation, as in other drug abuse disorder [4], and not pain hypersensitivity.
If this is happening in parietal cortex, we should expect to find the same kind of momentary adaptive neural modulation occurring in other cortical or sub-cortical components of the social brain network.
To date, however, all these important insights are derived from studies carried out in neuronal cells, and the implication of α-synuclein in autophagy modulation in cells other than neurons has not been investigated yet.
These results support an adverse role for oxidative stress in wound healing and tissue repair, and provide a rationale for the development of UA analogs in the treatment of wounds and for modulation of angiogenesis in other pathological conditions.
These results suggest that Notch signaling plays important roles in wound healing and tissue repair, and that targeting the Notch pathway might provide a novel strategy for treatment of wounds and for modulation of angiogenesis in other pathological conditions.
It is unclear if those who have pain after TKA have reduced conditioned pain modulation, as occurs in other postoperative conditions [ 38].
Some of these studies noted these modulations, whereas in others, they are obvious in the presented data.
While mTOR inhibitors show some potential as therapeutic agents, mTOR has multiple roles in cellular homeostasis, and thus mTOR inhibitors are likely to have side-effects due to modulations in processes other than autophagy.
The implementation of high frequency modulation and demodulation technique will be helpful for removing slow laser intensity noise as in other modulation transfer techniques [ 19].
3) Different modulation states might exist in other frequency bands mediating different functions in the brain.
