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Issues related to TP modulation in human tumour tissues, however, are still largely unknown.
The involvement of IIS modulation in human longevity is less clear [ 5].
To the best of our knowledge, this is the first demonstration of HIV-induced miR modulation in human MDDCs.
Transposable elements constitute nearly half of the primate genome and there is increasing evidence for their functional role in influencing expression and potential modulation in human pathology [ 78].
Given this assumption, we would expect a positive correlation of behavioral performance with the amount of task-dependent modulation in human MGB during speech recognition.
Data on changes in startle response in response to emotional state and its modulation in human pregnancy and puerperium are sparse.
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The specific contribution of afferent feedback from skeletal muscles to central command modulation in humans have been investigated by Amann et al. via attenuation of afferent feedback from skeletal muscles during a closed loop exercise task (i.e., time trials were subjects that regulated the power output to achieve the best possible time) [ 67].
Therefore, in order to determine the pathophysiological relevance of AP-1 down-modulation in human cardiac cells, we next analyzed the expression of various genes that had been reportedly demonstrated to be targeted by the AP-1 transcription factor and also be involved in cardiac disease.
This defines TSP-1 as a potential target for therapeutic immuno-modulation in humans during CLI.
Some previous studies have suggested that attention-related modulations in humans are confined to secondary auditory cortex [15], while others have suggested involvement of the primary auditory cortex [5], [8], [24].
To date, however, it has remained unknown whether and how MrD participates in pain modulation in the human brain in vivo.
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