Sentence examples for modulation in breast from inspiring English sources
Sulphoraphane therefore can be regarded as a potent inducer of apoptosis due to HSP modulation in breast cancer cells.
Overall, these data illuminated the importance of ESR1 modulation in breast cancer.
On the other hand, investigation into functions governed by gene modulation in breast cancer remains largely unexplored.
HRG is a ligand of the ErbB receptor family, and to our knowledge, this is the first report of an HRG-induced miRNA modulation in breast cancer.
However, our study is the first to show the relevance of miR-16 modulation in breast cancer models throughout a stimulus that is relevant to breast cancer pathophysiology.
As has been mentioned previously, GPER stimulation is involved in the transactivation of EGFR/ERK signaling and PI3K modulation in breast cancer cells (Filardo et al. 2002, Revankar et al. 2005).
Furthermore, SFN also decreased telomerase reverse transcriptase (hTERT) expression through promoter de-methylation and epigenetic modulations in breast cancer cells, suggesting that SFN may target other hypermethylated gene promoters that are dys-regulated during carcinogenesis and warrant further investigation.
This landscape of interaction between miRNAs and proteins reveals several intriguing relationships, including the fact that groups of miRNAs coordinately interact with groups of proteins, hence suggesting 'block interaction' as a mode of modulation of protein modules in breast cancer.
We found no evidence for expression modulation in the breast cancer cell lines, suggesting that such disease mechanism is more likely to operate in non-neoplastic epithelial or stromal cells or has been lost during in vitro propagation of the cell lines.
Modulation of FAS in breast cancer cell lines altered radiation response phenotype and enhanced radiation sensitivity in radioresistant basal cell lines.
Several preclinical studies from different laboratories have suggested that the CD40 signaling pathway plays a role in the modulation of chemosensitivity in breast cancer cells.
