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The Hybrid IMRT/VMAT technique can be implemented to find the optimal compromise between gantry-angle and intensity modulation degrees of freedom, dosimetric quality, and delivery efficiency.
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We measure a gene's functional importance in relation to cell survival by the essentiality of the essential genes and the toxicity modulation degree of non-essential genes.
Modulation includes degrees of obligation for commands and degrees of inclination in offers, and can be expressed by Finite modal operators or by "an expansion of the Predicator through verbal group complexing" ((Halliday & Matthiessen 2014): 178).
Specifically, we define a gene's toxicity modulation degree as the number of DNA-damaging treatments significantly affecting the deletion strain's fitness (toxicity modulation degree = 0 (no phenotype), 1, 2, 3, and 4).
The fan-out degree of every single lipid component in these graphs shows us the modulation degree with a given treatment.
The proposed modulation scheme provides additional degrees of freedom for GNSS signal design.
Then, we correlated the expression of TfR with the degrees of modulation.
Whereas iron II) glycine sulfate was able to increase sensitivity of tumor cells to artesunate in most cell lines, there was no correlation between the IC50 values and high degrees of modulation by iron II) glycine sulfate.
Cell lines with high TfR expression significantly correlated with high degrees of modulation indicating that high TfR expressing tumor cells would be more efficiently inhibited by this combination treatment than low TfR expressing ones.
Furthermore, degrees of modulation (IC50 for artesunate divided by the IC50 for artesunate plus iron II) glycine sulfate) did not correlate with IC50 values for artesunate, e.g. cell lines with high IC50 values for artesunate were not more modulated by the addition of iron II) glycine sulfate than cell lines with low IC50 values for artesunate (Table 1).
We found that cell lines with high TfR expression significantly correlated with high degrees of modulation (Table 2) indicating that high TfR expressing tumor cells could be more efficiently inhibited by a combination of artesunate and iron II) glycine sulfate than low TfR expressing ones.
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