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Once a certain type of food is discovered and the collected nectar passes from foragers to the rest of the colony, this modulation could have profound effects on the overall balance between collection and processing capacity of the entire colony in an ever-changing floral market foraging environment.
However many of its substrates have roles in cell growth and oncogenesis, raising the possibility that CDK5 modulation could have therapeutic benefit.
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In the present study, the observed RSA modulations could have contributed to greater tolerance of transient or prolonged drought stress because of increased root branching in the soil upper layers (topsoil foraging) or, to a lesser extent, a longer primary root (deep soil foraging), respectively.
Molecular chaperones have central roles in each of the arms of the PN (protein synthesis, folding, disaggregation, and degradation), leading to the proposal that modulation of chaperone function could have therapeutic benefits for the large and growing family of diseases of protein conformation including neurodegeneration, metabolic diseases, and cancer.
miR have multitarget characteristics and can regulate groups of genes; thus, low-level modulation from individual miR could have an additive effect on multiple gene targets [ 9].
These studies illustrate the importance of IL-6 regulation in normal cell function and suggest that any modulation of its expression could have important pathologic consequences.
These results show that frataxin participates to the hypoxia-induced stress response in tumors, thus implying that modulation of its expression could have a critical role in tumor cell survival and/or progression.
Since MET amplification plays an important role in the resistance to anti-EGFR agents, a modulation of these miRNAs could have therapeutic applications to sensibilize lung tumors to TKI therapy [ 77].
Nevertheless, when we take into account the specific regulation of mitophagy in different cell types, this opens up an attractive avenue for therapeutic intervention where modulation of the process could have the potential to target certain cell populations without inducing detrimental effects on the remaining organs and tissues of the brain/body.
Experimental analyses of these networks should consider that the modulation of a single motif could have effects across the network.
For an object closer to the mouse, the myopic mouse could have a modulation as high as 0.75 for the cone Nyquist limit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com