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Safety, tumoral pharmacodynamic (PD) modulation, correlation to surrogates (PBMC), and the relationship between PK and PD were study endpoints.
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Real-time PCR confirmed the modulation of St14 transcript levels and strong correlation to Krt-19 and also showed a significant up-modulation and strong correlation to Spint1 encoding HAI-1, a cognate inhibitor of matriptase.
Negative correlation to both induced and spontaneous alpha modulations were found predominantly in low-level visual areas in the occipital cortex (see Fig. 4B).
Finally, significant modulation correlations were found between ERD% and hemodynamic measures despite the absence of significant amplitude correlations.
Additionally, EEG alpha at 11.5 Hz at a parietal electrode (P8) showing negative correlation to subjects' subsequent recall [19] was used to evaluate the influence of EEG power modulation on the predictability of the model.
"I see a correlation to golf.
Direct correlation to greater mental illness.
The latencies of the modulation of these cells were complementary, as were their correlations to behavior.
and try to choose the modulation sequences to minimize the correlation coefficient γ i subject to the following two constraints: 1 P ∑ k = 1 P c i ( k ) 2 = 1, (3.21) c i ( k ) 2 ≥ τ > 0, ∀ 1 ≤ k ≤ P (3.22).
This would suggest that effects due to emotional arousal should be greater for highly unpleasant and pleasant stimuli, which were rated as slightly more arousing than stimuli evaluated as less positive/negative [ 44]. 2) Secondly, HR, EMG, and SCR should show a modulation in correlation with emotionally relevant, arousing and pleasant or unpleasant stimuli.
The strict deterministic character (at the population scale) of the fine modulation correspondent to the minor components is proven by the strong correlations existing between partially independent gene expression panels.
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CEO of Professional Science Editing for Scientists @ prosciediting.com