Sentence examples for modulation by alternative from inspiring English sources

Many recent structures reveal metal ion sites that control or are controlled by protein conformational change, including modulation by alternative splice variants and striking conformational changes.

The important point is that stress-induced modulation by alternative splicing of the expression of WSB1 isoforms is very similar to what we observed during xenograft tumor progression.

Using PTC's proprietary drug discovery platform technology referred to as GEMSAS (Gene Expression Modulation by Small-molecules – Alternative Splicing™) we have designed and conducted a high throughput screen of our compound library.

However, CQ could also act by alternative pathways involving modulation of cellular biometal metabolism.

Therefore, modulation of alternative splicing by differential gene methylation could lead to differentiation-related differences in the resulting proteins.

Savaldi-Goldstein S, Aviv D, Davydov O, Fluhr R. (2003) Alternative Splicing Modulation by a LAMMER Kinase Impinges on Developmental and Transcriptome Expression.

The aspect of mechanistic process probed here is if the 'spatio-temporal' idea of obstruction of the active site by higher concentration of substrates (or an allosteric modulation by excess substrate at an alternative enzyme binding site), as advocated erstwhile, and as is depicted in Figure 1, provides an adequate explanation to the 'substrate inhibition' kinetics.

Palaniyandi, P., Lakshmanan, M. "Secure digital signal transmission by multistep parameter modulation and alternative driving of transmitter variables," International Journal of Bifurcation & Chaos in Applied Sciences & Engineering, vol.11, no.7, pp.2031-2036.

We have shown that exon-skipping ASOs can be used to phenocopy certain diseases by gene-targeted modulation of alternative splicing.

Raver1 is a member of the heterogeneous nuclear ribonucleoprotein family (hnRNP) that shuttles between the nucleus and cytoplasm and is involved in modulation of alternative splicing mediated by PTB (Polypyrimidine Tract-Binding protein) (Gromak et al., 2003).

To improve these properties, the sandwich structured carbon films with different modulation ratios were introduced on silicon (100) wafers by alternative irradiation (ion/electron/ion) technique in ECR sputtering system.