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Most importantly, both phenomena point toward the importance of the endogenous opioid system in pain modulation, as indicated by blockade of the effect in the presence of the opioid antagonist naloxone [3], [5], [6].
Baseline fatigue sensation, measured by a visual analogue scale before the experiment, was associated with the decrease in parasympathetic sinus modulation, as indicated the by ratio of low-frequency component power (LF) to high-frequency component power (HF), during the KPT.
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In five healthy individuals, Mao and Evinger (2001) used associative high-frequency stimulation (HFS) of the supraorbital nerve to induce LTP- and LTD-like changes in the excitability of the trigeminal blink reflex circuit, as indicated by modulation of the R2 response [13].
The present study demonstrated that GITR triggering in poststroke mice enhanced, and its blocking ameliorated the poststroke inflammatory response as indicated by modulation of cytokines, such as IFN- γ, TNF- α and IL-10.
However, in most cases a synergistic effect was demonstrated when cells were exposed to both compounds, implying a potent effect on oxidative stress as indicated by the modulation of superoxide dismutase.
Moreover, the described alterations are caused by the modulation of Dpp/BMP2 signalling by dTIEG as indicated by the changes observed in the expression of Dpp target genes sal and omb.
Furthermore, such modulation appears more sparse and heterogeneous as indicated by a lack of GO enrichment.
Furthermore, electrophysiological measures permit one to examine whether structural and emotional aspects of face encoding are serial versus parallel processes as indicated by a modulation of the N170 response to faces.
Importantly, favorable physiological activity of potential therapeutic value was maintained in this variant trophic factor with significant target activation in GDNFv recipients as indicated by dopamine turnover modulation.
At the same time, it is possible to hypothesize a modulation of TLR signaling throughout different ways, as indicated in Figure 2 [ 19, 24, 59].
As indicated in many previous studies, hierarchical modulation for unicasting induces cooperative communications.
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