Sentence examples for modulating the viral from inspiring English sources

Therefore, we tried to examine the effect of exogenous expression of IRF7 under the assumption that IRF7 is a potent type I IFN inducer and capable of modulating the viral propagation in hepatocytes infected with HCV.

The enhanced accumulation of MCMV-reactive CD8+ T cells might have been a consequence of modulating the viral load.

On the other hand, we cannot exclude that by suppressing HIV-1 production miRNA-29a could regulate viral gene expression, modulating the viral life cycle and promoting the onset and maintenance of latency.

Genetic tuning of the virus through the incorporation of specific nucleotide substitutions and gene reassortments are responsible for modulating the viral fitness, level of pathogenicity, and transmissibility on different host species [ 9, 21, 22].

CD8+ T cells contribute to the control of HIV, but it is not clear whether initial immune responses modulate the viral set point.

Therefore, it was hypothesized that the reassortments of viral polymerase genes in the pandemic H2 and H3 might modulate the viral polymerase activity, thereby helping the progeny viruses to adapt to humans [45], [46].

Viral miRNAs can regulate both cellular and viral gene expressions through the regulation of cellular elements involved antiviral responses, simulating cellular miRNAs, or targeting their own viral messenger RNAs to modulate the viral replication cycle.

Our laboratory identified thyroid hormone responsive elements (TREs) in several HSV-1 regulatory regions and one of them is located in the LAT regulatory sequence, suggesting that thyroid hormone (T3) could have roles in the transcriptions of LAT and neighboring regions and therefore modulate the viral latency and reactivation.

12 SLFN11 is induced directly by pathogens via the interferon regulatory factor 3 (IRF3) pathway and was shown to bind specific tRNAs modulating the translation of viral proteins without affecting the translation of cell proteins.

The most prominent viral genetic association with outcome of therapy is that HCV genotype 1 is much less sensitive to treatment than genotypes 2 and 3, but genetic differences below the genotype level also influence outcome of therapy, presumably by modulating the ability of viral genes to blunt antiviral immune responses.

It benefits have also been documented to help with diabetes, normalizing blood pressure, modulating the endocrine system, viral infections and even helps conditions such as rheumatoid arthritis due to its anti-inflammatory effects.[citation needed].