Sentence examples for modulating the translation from inspiring English sources

This is another indication that the differential usage of synonymous codons can influence the structure/function of the translated proteins, possibly by locally modulating the translation efficiency/speed, and not only on their overall concentration.

Each pre-miRNA can have multiple mature miRNAs (18 24 nucleotides in length) which are incorporated into a protein complex, responsible for modulating the translation efficiency of multiple targets.

These novel types of S. japonicum miRNAs could play important roles in development, maturation and host-parasite interplay via modulating the translation and/or mRNA stability of target genes.

While previous papers [20] [22] documented the participation of the proteasome degradation system, our study shows that other mechanisms are involved in the regulation of DAPC, particularly, the microRNA system plays an important role by modulating the translation of the mRNA of some DAPC components.

12 SLFN11 is induced directly by pathogens via the interferon regulatory factor 3 (IRF3) pathway and was shown to bind specific tRNAs modulating the translation of viral proteins without affecting the translation of cell proteins.

These proteins interact with an extensive variety of cellular RNAs and exhibit activities in two broad categories: i) to promote the metabolism of nascent pol III transcripts, including precursor-tRNAs, by binding to their common, UUU-3′OH containing ends, and ii) to modulate the translation of certain mRNAs involving an unknown binding mechanism.

For example, it influences the status of pro-inflammatory cytokines in central nervous system and modulates the translation of methionine synthase by the internal ribosome entry site (IRES) [14], [15].

For example, SNPs occurring in 3'-UTR SNPs modulate the translation process by impacting mRNA transport [28], interference with the compartmentalized expression of tissue-specific genes in particular cellular loci [29] and altering mRNA stability [30].

TRAP also modulates the translation of the trpE and trpD genes by binding to the complete trp-mRNA.

15– 16 It has been recognized that G-quartet candidate sequences are frequently found in 5'UTR, and in some cases modulate the translation efficiency of the cognate transcripts.

In turn, HuR stabilized and/or modulated the translation of target mRNAs encoding numerous cytokines, such as TNF-α, IL-6, IL-13, interferon γ, and GM-CSF.