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Recent studies have revealed that parkin plays general role for mitochondrial motility and mitochondrial quality (Bingol et al., 2014; Gegg et al., 2010; Matsuda et al., 2010; Narendra et al., 2008; Tanaka et al., 2010) through modulating the stability of Miro (Wang et al., 2011b) and many other mitochondrial proteins (Chen and Dorn, 2013; Gegg and Schapira, 2011).
By modulating the stability of the hairpin any OCP can be fine tuned for ligation specificity.
However, beyond the sequence-level information, structural mechanisms for different α chains in modulating the stability and conformation of a collagen triple helix are unclear.
Recent research also suggests that this might be mediated by SUMOylation, a process that plays a part in modulating the stability of the FOXM1 protein [75].
Although much is known about how dosage compensation is established, the consequences of modulating the stability of dosage compensation postembryonically are not known.
We report that TSA enhanced acetylation as well as the stability of the ERα protein by modulating the stability of p300.
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The introduction of a spacer between the chelator and the peptide is an important feature since it can modulate the stability, affinity, and pharmacokinetics of the bombesin derivatives.
Depending on the nature of this side-chain, it is possible to modulate the stability of the hexamer in a predictable manner.
The development of small molecules that modulate the stability of G-quadruplex structures has a potential therapeutic interest in cancer treatment and prevention of aging.
miRNAs comprise a class of ∼22 nt noncoding RNAs that modulate the stability and/or translational potential of their mRNA targets.
Interestingly, the colloidal stability studies indicate that it is possible to modulate the stability, hence the delivery of sorafenib from the SLNs to the physiological environment, depending on the nucleolipid used for the stabilization of the SLNs.
More suggestions(15)
modulating the data
modulating the steady
modulating the strength
modulating the architecture
modulating the pulse
modulating the devil
modulating the via-hole-length
modulating the behavior
modulating the activity
modulating the amount
modulating the feed
modulating the propagation
modulating the sound
modulating the incoming
modulating the neck
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