Exact(1)
On the other hand, blocking (or negatively modulating) the small conductance SK potassium channel increases the tendency to burst rhythmically both in vivo [17, 18] and in vitro [5, 19, 20].
Similar(59)
It also indicates that suggestions can modulate the small effect of meditation on verbal fluency.
Furthermore, Sema3E/PlexinD1 binding mediates the disassembly of actin filaments by PAK activation by modulating the activity of small GTPases in several cell types (see ref. 36 for review).
These genes are believed to play a role in modulating the concentrations of the small chain acyl carnitines.
This study demonstrates the in vitro feasibility of modulating the hydrodynamic radius for small peptide chaperones by seamless fusion with protein polymers; furthermore, they may have therapeutic applications in diseases associated with oxidative stress, such as AMD.
Moreover this can be achieved by modulating the activities of a small number of specific growth factors either through their addition to the medium or their pharmacological inhibition (for summary see Figure 5).
In fact, thanks to these unique capabilities, it has been possible for example to realize original investigations on the thermoregulatory processes modulating the blood flow of small muscle masses in humans [ 10] or to observe blood flow pulsations in human bones [ 11, 12].
The pharmacophore model based virtual screening unveils two lead compounds from the TIMBAL database of small molecules modulating the targeted protein-protein interactions.
Therefore, the strategy on basis of modulating the π-bridge units of small molecules can effectively change the performance of HTMs and thereby provide a useful guideline of π-bridge screening for the design of excellent HTMs in PSC applications.
TolR-ExbD proteins are membrane-bound transport proteins essential for ferric ion uptake in bacteria [ 62], and small RNAs modulating the free intracellular iron pool have indeed been identified in other bacteria (e.g RyhB, [ 63]).
It has been reported that nm23-H1 inhibits cell migration and cancer metastasis by modulating the activity of Rho-family small GTPase enzymes, which are known to play a key role in the actin cytoskeleton dynamics required for cancer cell migration and invasion [ 34].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com