Sentence examples for modulating the risk from inspiring English sources

Last, common variants of small effect size, modulating the risk for PD, have been identified by genome-wide association studies in more than 20 chromosomal loci.

Polymorphisms in TLR genes may shift balance between pro- and anti-inflammatory cytokines, modulating the risk of infection, chronic inflammation and cancer.

Dysregulation of the TLR4 signaling owing to single nucleotide polymorphisms (SNPs) may alter the ligand binding and balance between pro- and anti-inflammatory cytokines, thereby modulating the risk of chronic inflammation and cancer.

The inferred allele combination constructed from the COL5A1 BstUI RFLP – IL1β −31 T → C – IL1β −511C → T – IL6 − 172G → C – IL1RN VNTR is associated with AT (p = 066005) and suggests the potential interactions of these respective sequence variants in modulating the risk profile of developing AT.

In this study we evaluated the combined effect of ten common genetic variants, with known modest effects on the hemostatic balance (listed in Table 1) [12] [21]–[21], in modulating the risk of development of MI.

Here we describe the KIR and HLA gene content among several mother-infant HIV-1 cohorts, in order to investigate if KIR genes and/or KIR genes together with their known HLA ligands may play a role in susceptibility of infants to HIV-1 infection and/or in modulating the risk of maternal HIV-1 transmission to the infant.

In the present study, aiming at elucidating the role of oipA genetic diversity in modulating the risks of PUD and/or GC, we performed a meta-analysis to investigate the association between the presence/absence and on/off status of oipA gene and PUD and GC risks.

miRNA studies provide mechanistic insights into genetic regulations that may modulate the risk of ASD.

Current evidence suggests that immune processes modulate the risk for cardiac involvement in HIV-infected persons.

XRCC1 is a scaffold protein critical for BER for which polymorphisms modulate the risk of cancer.

It was reported that a variant of the ETa receptor gene modulates the risk for migraine [70].