Sentence examples for modulating the recruitment from inspiring English sources

Complementary studies of inflammation in Drosophila embryos and zebrafish larvae allow us to live image the wound inflammatory response and provide opportunities to dissect the genetics of inflammatory cell recruitment to wounds, which in turn may allow us to identify gene targets for therapeutically modulating the recruitment of inflammatory cells and thus improving adult healing.

We tested the ability of NF-Y binding in modulating the recruitment of different modified histones onto its target DNA also in muscle of mdx mice that represent an animal model for human Duchenne and Becker muscular dystrophy.

and suggests that these RJ-derived medium chain fatty acids, structurally entirely different from E2, mediate estrogen signaling, at least in part, by modulating the recruitment of ERα, ERβ and co activators to target genes (Fig.6.II).

Our data propose a possible molecular mechanism for the estrogenic activities of RJ's components which, although structurally entirely different from E2, mediate estrogen signaling, at least in part, by modulating the recruitment of ERα, ERβ and co-activators to target genes.

Targeted therapies modulating the recruitment and activation of these cells could potentially delay coronary allograft vasculopathy and improve long-term survival of heart transplant recipients.

Previous studies on chemokines and their receptors in modulating the recruitment of leukocytes at the sites of inflammation suggested that targeting these molecules with engineered agents might have therapeutic utility in down-modulating inflammatory responses.

Various factors in the tumor microenvironment can modulate the recruitment and retention of BM-derived cells during the development of the tumor vasculature [37].

Indeed, epithelial cells can secrete an array of proinflammatory molecules that modulate the recruitment and functioning of immune and inflammatory cells [1].

A recent study demonstrated that PlGF, a ligand for VEGFR1 as well as Neuropilins 1 and 2 (NRP1/2), significantly modulated the recruitment of macrophages, tumor growth and local invasion [7].

Thus, one way that menin regulates expression of Hoxa9 and other Hoxa cluster genes may be to modulate the recruitment of endogenous MLL and MLL-AF9 to a particular locus to alter histone modifications.

Therefore, it is tempting to speculate that sHLA-G, by dampening CXCR3 mediated chemotaxis, modulates the recruitment of these cell populations to granulomatous mycobacterial lesions, perhaps limiting excessive tissue damage.