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In particular, the authors show that exosomes derived from breast cancer cells, and sera from patients, contain DICER and process pre-miRNAs into mature miRNAs, thus modulating the recipient cell phenotype.
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Exosomes may transfer unique patterns of their contents to neighboring cells and may therefore induce the phenotypic modifications in recipient cells, subsequently modulating the microenvironment [ 37, 38].
The canvas grins through, modulating the whiteness.
Targeted therapies modulating the recruitment and activation of these cells could potentially delay coronary allograft vasculopathy and improve long-term survival of heart transplant recipients.
In addition, EVs from renal cells were shown to modulate the function of the recipient cells.
Previous studies have reported that the transfer of genetic material from one species to another may modulate the cellular functions of the recipient species50,51.
These EVs were able to modulate the levels of radical production of the recipient distal tubular cells, transferring an anti-inflammatory message [ 50].
However, when used in transplant recipients or for other indications, agents that suppress or modulate the immune system (immunomodulators) have been associated with an increased risk of lymphoma.
Inside the recipient cells, the pheromone binds to the plasmid-encoded cytoplasmic protein TraA, able to recognize specific DNA sequences and to modulate the conjugation process.
We modulate the temperature.
Saccharin directly modulates the microbiota.
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