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To explore how PUM2 stabilizes Aurora-A, we determined whether the interactions between Aurora-A and PUM2 are necessary for modulating the protein stability of Aurora-A.
IL-16 might also inhibit the fusion of T. whipplei phagosomes with lysosomes by modulating the protein level of cathepsin D present on macrophages.
The different response types can also (trivially) be obtained by modulating the protein concentrations accordingly.
The principle of the kit is to determinate protease activity after modulating the protein through SIRT-1-mediated deacetylation.
A second mechanism through which SIRT1 has been shown to influence neurodegenerative disease is by modulating the protein turnover of proteotoxic species by direct deacetylation.
Chemoresistance is reversed by Qct, and we therefore propose a mechanism by which Qct abrogates the inhibitory effects of ΔNp73 by modulating the protein and altering its localization.
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Since mechanical oscillations are local, can we modulate the protein folding & its complex formation from isolated proteins using megahertz electromagnetic signals, non-locally?
Therefore, disulfide bond reduction modulates the protein folding/misfolding landscape by entropically stabilizing disordered states, including the U and transition state of aggregation.
We identified realistic conditions under which mRNA lifetime and transcriptional pauses modulate the protein expression noise initially introduced by the promoter architecture.
NGM Biopharmaceuticals, Inc. has filed a non-provisional patent application entitled "Compositions and Methods for Modulating Body Weight" (PCT/US2017/020753), which discloses the GFRAL GDF15 protein complex, and methods of identifying agents that may modulate the protein complex interaction(s) and potential uses of those agents to control body weight.
Sp1 is subjected to several PTMs, which modulates the protein level, the DNA-binding activity or the transactivation potential of Sp1 (Chang and Hung, 2012).
More suggestions(15)
modulating the relationship
modulating the cancer
controlling the protein
adjusting the protein
modulating the gene
modulating the enzyme
affecting the protein
modulating the body
modulating the spike
modulating the strength
modulating the architecture
modulating the pulse
modulating the via-hole-length
modulating the behavior
modulating the activity
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