These inhibitors indirectly affect Ca2+ signalling by modulating the long-lasting plateau phase (Beeton et al., 2001).
These findings suggest a potential role for MRP1 and MDR1 SNPs in modulating the long-term outcome of relapsed and/or refractory myeloma patients treated with PLD + bortezomib.
Recent studies have implicated E2 and ERα as modulating the long-term ability of glucose to stimulate insulin production and release from pancreatic β-cells (58).
However, we cannot completely exclude that extremely weak, dynamic interactions can occur between FG repeats, and indeed such interactions may modulate the long distance distribution of FG repeat regions in the NPC.
We also provide evidence that Rtn4r deficiency can modulate the long-term behavioral effects of transient postnatal N-methyl-D-aspartate (NMDA) receptor hypofunction.
In prefrontal cortex (PFC) and striatum DA is involved in the expression of synaptic plasticity by modulating the amount of long-term potentiation (LTP) and depression (LTD) of glutamatergic synapses [15], [16], [17], [18], [19].
By priming the host response, type I interferons can, in turn, enhance and modulate the inflammatory cellular responses to other molecules long implicated in modulating the pathogenesis of autoimmune diseases, such as TNF, IL-1 and IL-6, IFNγ, and TLRs [ 23, 35, 46, 47].
EPO treatment enhances hippocampal long-term potentiation by modulating the plasticity, synaptic connectivity and activity of memory-related neuronal networks (Adamcio et al., 2008) and improves the operant conditioning stability of cognitive performance in healthy mice (El-Kordi et al., 2009).
The canvas grins through, modulating the whiteness.
Thus, the regular caffeine intake by coffee drinking may effectively modulate the encoding and long term retrieval of memories by enhancing sustained attention [ 32, 33].
