Antidepressants like venlafaxine and sertraline expected to improve Parkinsonism like symptoms by modulating the levels of various neurotransmitters.
Monoamine oxidase A is the metabolic enzyme of neurotransmitters and the uVNTR polymorphism located in its promoter affects its transcriptional activity modulating the levels of monoamines.
Monoamine oxidase A is the metabolic enzyme of neurotransmitters, and uVNTR polymorphism, located in the promoter region, affects its transcriptional activity modulating the levels of monoamines.
miRNAs control temporal and spatial gene expression by both accelerating the decay of mRNAs from previous developmental stages and modulating the levels of actively transcribed genes.
These results show that molecular weight provides for tunability of polymer nanotube thickness in AAO templates, that there is excellent agreement in confinement effects measured by DSC and by ellipsometry, and that Tg can be tuned by modulating the levels of interfacial, polymer-substrate interactions by using surfaces with different chemical or crystallographic properties.
BMMSCs and WJMSCs could probably influence lymphoproliferation responses uniquely by differentially modulating the levels of key immune activation markers which contribute to the development of the immune response.
This can be achieved, for instance, by modulating the levels of NUMB, by RNA interference and/or overexpression experiments, and checking the levels of TP53.
It has been suggested that one of the ways in which Mtb represses the pro-inflammatory responses at the site of infection is by modulating the levels of Ca2+ [34].
In addition, it is widely believed that factors such as calorie restriction may extend the lifespan of organisms, in part, by modulating the levels and expression of particular genes and pathways [1], [2].
Interestingly, modulating the levels of PI 3,4,5 P3 by overexpressing PTEN or its phosphatase-deficient mutant PTEN(G129E) revealed a correlation between PI 3,4,5 P3 levels and macropinosome formation.
This is consistent with the previous observation that IL-4 regulates cytotoxic CD8+ T cell responses by modulating the levels of B7-1 and B7-2 on DC [21].
