(Hamilton goes on to chastise Seabury: "Don't modulate the key and not debate with me!" he insists, a line that encapsulates the show's knowing interplay between musical form and political content).
Furthermore we find that this morphogenetically-regulated tissue packing modulates the key cell polarity protein Crumbs, which in turn is required for tissue packing, suggesting that it may participate in the molecular mechanism/s underlying the described tissue organisation.
By unraveling the basis of carotenoid biosynthesis it has become possible to modulate the key metabolic steps in plants and thus increase the nutritional value of staple crops, such as rice (Oryza sativa), maize (Zea mays) and potato (Solanum tuberosum).
Considering the central importance of the UPR in regulating cell survival and death, evidence is emerging that cells evolve feedback regulatory pathways to modulate the key UPR executors, however, the precise mechanisms remain to be elucidated.
Considering the central importance of UPR in regulating cell survival and death [1], [2], [18], [19], the prediction is that cells will evolve feedback regulatory pathways to modulate the key UPR executors.
Several studies have indicated the possibility of using extracts from blackcurrant to beneficially modulate the key markers of the health status of a consumers' body [ 1, 3, 5].
Manipulation of competing metabolic pathways by modulating the certain key enzymes such as hydrogenase and nitrogenase may enhance the evolution of H2 from photoautotrophic cells.
The anti-atherogenic cytokine, TGF-β, plays a key role during macrophage foam cell formation by modulating the expression of key genes involved in the control of cholesterol homeostasis.
Most researchers believe that two commonly administered drugs, donepezil and memantine, which aim at modulating the activity of key neurotransmitters, have limited short-term effect and do nothing to slow the progression of the disease.
In plants, the majority of genes regulated by miRNAs are transcription factors; thus miRNA activity is particularly wide-ranging and regulates entire gene networks during development by modulating the expression of key regulatory genes, including transcription factors as well as F-box proteins.
