Sentence examples for modulating the highs from inspiring English sources

Back then, he said, "so much of our efforts were directed at modulating the highs".

Post-translational modifications of histones acetylation, phosphorylation and methylation locally modulate the higher order nucleosome structure.

In this study, we hypothesized that varying the cell adhesion properties of ELR-hydrogels could modulate the high angiogenic potential of adipose tissue-derived stromal vascular fraction (SVF) cells, predominantly composed of endothelial/mural and mesenchymal cells.

In particular, since STD is a mechanism that usually modulates the high frequency inputs, one can wonder about its effect in the SR curve.

We also found that the UPR pathway, through the IRE1α/XBP1 axis, modulated the high-level expression of ERLIN2 protein.

Of note, CPT-11, modulated the high mobility group box-1 pathway, confirming the central role that it plays in the induction of anti-cancer activity by chemotherapeutics through activation of innate immunity [ 26, 27].

Following Equation 8, for the layer pair of molybdenum and silica, where acoustic impedances are 66.2 MRayl and 13.1 MRayl, respectively, the fixed impedance ratio is 5.1, and the same impedance ratio can be obtained using PS layers of 30%and75%75 %, so, by modulating the porosity, very high reflectivity values can be achieved.

Sensing of low phosphate availability also triggers long distance signals to systemic tissues that activate phosphate homeostasis mechanisms via increased phosphate transport, recovery, and recycling by modulating the expressions of high-affinity transporters, secreted phosphatases, and phospholipid catabolism enzymes.

Because both monomers in the PEGDMA- co-EGDMA system undergo cross-linking reactions, tuning of the matrix stiffness is realized by modulating the ratio of the high molecular weight PEGDMA monomer relative to the low molecular weight EGDMA monomer.

Vanillin decreases HbS polymerisation by allosterically modulating the HbS molecule to the high affinity state, and concurrently inhibiting the T state HbS polymerisation.

Taken together, these results suggest a central role for IL-1 in modulating the blood pressure response to high lipids and that this is via a selective reduction in bioavailable nitric oxide.