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Engineering commensal organisms for challenging applications, such as modulating the gut ecosystem, is hampered by the lack of genetic parts.
Supplementation with the herbal extract YGD reduced energy and macronutrient intake by modulating the gut hormones in overweight and obese women.
We have previously shown that oligosaccharides issued from inulin-type fructans counteracted obesity and metabolic alteration development upon high-fat feeding including dyslipidemia and diabetes, by modulating the gut microbiota9,10.
The results observed in the in vitro model SIMGI indicate that it can be used as a tool for studying the effects of diet or food components on modulating the gut microbiota and its metabolic activity.
Therefore, the addition of Astragalus to feed may be beneficial for modulating the gut microbiota of young hens.
Clearly, the gut microbiome is emerging as an essential component in the development of personalized medicine and modulating the gut microbiome has the potential to become a very attractive approach to managing drug efficiency and safety on the level of the individual.
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Probiotics have the potential to healthfully modulate the gut microbiome.
Therefore, the aim of this study was to modulate the gut microbiota by antibiotic therapy to investigate effects on parameters reflecting cholesterol metabolism and oxyphytosterol concentrations.
Meanwhile, CM and PR significantly modulated the gut microbiota of the high-fat diet (HFD) treated mice, similar to metformin, and CM-PR reversed the overall microbiota composition similar to the normal chow diet (NCD) treated mice.
Here we review the mechanisms by which the host modulates the gut community composition during health and disease, and we discuss prospects for antibiotic and probiotic therapy for restoration of a healthy intestinal community following disruption.
Pharmacomicrobiomics thus may have at least two global clinical applications: 1) to combine personal microbiome and genetic profiles to better predict an individual's medication response; and 2) to modulate the gut microbiome to improve drug efficacy on the individual level.
More suggestions(16)
modulating the pulse
modulating the association
modulating the devil
modulating the via-hole-length
modulating the behavior
modulating the activity
modulating the amount
modulating the feed
modulating the propagation
modulating the sound
modulating the research
modulating the incoming
modulating the neck
modulating the flux
modulating the tone
modulating the drinking
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