Sentence examples for modulating the gene from inspiring English sources

ALK-5 receptor propagates an intracellular signaling that forms a protein complex capable of reaching the nucleus and modulating the gene transcription.

The sensing of the local density may occur either by a specific mechanism that targets the activity of myogenic genes or by simply modulating the gene expression noise in a density- and phenotype-dependent way.

Moreover, AGEs severely affect cellular metabolism by disrupting adenosine triphosphate production, enhancing oxidative stress, and modulating the gene expression of anti-angiogenic and anti-inflammatory genes.

This response seem to be rationale: among the metabolic factors modulating the gene expression of NR, NO3- and aa concentration are very important.

IL-1β plays a key role in obesity-induced inflammation [ 39] and inflammation-related carcinogenesis by modulating the gene expression involved in proliferation, survival, and angiogenesis [ 40].

Meanwhile, IL-1β suppresses UGDH gene expression through activating SAP/JNK and p38 MAPK pathways and subsequently modulating the gene expression of UGDH's trans-regulators including Sp1, Sp3 and c-Krox.

Thus, it is likely that the bone microenvironment plays a considerable role in modulating the gene-expression profiles of breast cancer cells in emerging bone metastases.

The same seed oil also generated drastic effect in modulating the genes that code for LDH in female subjects.

This study also revealed that the antisickling properties of these plants might function by modulating the genes responsible for LDH synthesis in both sexes.

This is obviously due to the fact that the seed oil could only generate a mild effect in modulating the genes that coded for LDH in male.

It is well established that although the original addictive drugs, reagents or factors are diverse, in view of molecular mechanisms, they could finally induce addiction by modulating the genes in the brain (Nestler, 2005).