Sentence examples for modulating the equilibrium from inspiring English sources
The connection of MAM-localized ACAT1 to AD is intriguing: the enzyme is absolutely required for the generation of Aβ, by modulating the equilibrium between free and esterified cholesterol (Puglielli et al, 2001, 2003, 2004; Pottekat and Menon, 2004), presumably as a result of its affects on APP processing (Huttunen et al, 2009a, 2009b; Bryleva et al, 2010).
Since the IRE1α-XBP1 is also involved in the production of a potent regulator for osteoclast differentiation, interferon beta [ 1, 2], the IRE1α-XBP1 pathway may be an attractive molecular target in modulating the equilibrium between bone formation and bone resorption under pathological conditions.
One study concluded that ClpXP operates catalytically to degrade FtsZ polymers and monomers, thereby modulates the equilibrium between free and polymeric FtsZ required for Z-ring assembly in an ATP-dependent manner [19].
To evaluate whether DMPK could have an impact on cell viability by modulating the mitochondrial redox equilibrium, we placed cells in a medium containing pyruvate and glutamine, but devoid of serum and glucose.
Such experiments will also be useful to determine how the relative affinity and concentration of an analogue peptide can be used to modulate the binding equilibrium, cytokine expression profile and T helper phenotype appropriately for treatment.
The equilibrium between receptor ubiquitylation and sumoylation is probably important in modulating the signaling cascade of IL-1, esthelishinumber number of receptors present on the cell surface.
Thus, these compounds, together with cTnI147−163, may exert their effects by altering the dynamic equilibrium between closed and open cNTnC conformations, enhancing the affinity for cTnI and thereby modulating the calcium sensitivity of troponin.
The canvas grins through, modulating the whiteness.
By modulating the flux through the loop,the cavity frequency is modulated.
By modulating the sound, that pocket can be moved around, changing the position of the bead.
The system works by modulating the LED lighting in your home or office.
