Sentence examples for modulating the disease from inspiring English sources

It is hypothesised that host innate immune response factors are involved in modulating the disease outcome and the expression levels of genes involved in this response could be used as early prognostic markers for disease severity.

The efficiency of activating latent transforming growth factor (TGF -β1 in sysTGF -β1upus erythematosus (SLE) may control the balance between inflammation and fibrosystemiculupusg therythematosusnotype.

As shown in our study, there could be considerable role of pre-existing T cellular immunity in modulating the disease severity of pandemic strains even in the absence of pre-existing neutralizing antibodies.

Currently, many health policies, including those in the environmental health arena, are formulated and implemented with only a limited foundation in understanding the role of the environment in causing or modulating the disease process.

Thus, in conjunction with conventional indicators, quantifying the disturbed nature of cytokine action in SLE could lead to approaches that objectively characterize disease status at the level of single-cell signaling states and may point to therapies that safely modulate the disease by modifying cell and cytokine responses.

Therefore, the degree of reduction of C9orf72 may well modulate the disease phenotype.

This information may contribute to the development of drugs that can selectively modulate the disease process.

Steroids such as dehydroepiandrosterone (DHEA), glucocorticoids, androgens and oestrogens have been shown to modulate the disease process in RA [ 2].

It is possible that even initiating a therapeutic within this timeframe is too late to modulate the disease pathways.

In the present review, we describe how the genetic background of these models and intervention protocols modulated the disease profile they project.

However, the identified genetic modifiers allow the characterization of biological pathways that modulate the disease and, in some cases, discovery of tractable therapeutic targets.