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HSA also could protect cells against oxidative stress by modulating the cellular GSH level.
This review highlights the cellular uptake routes most relevant to the field of non-targeted nanomedicine and presents an account of ligand-targeted nanoparticles for receptor-mediated cellular internalization as a strategy for modulating the cellular uptake of nanoparticles.
We show that mechanical forces play an important role in modulating the cellular response to infection and may determine disease pathophysiology.
Surprisingly, our data also suggest that the E3 ubiquitin ligase activity associated with the RING finger domain is not directly required to inhibit the activation of IRF3 but instead plays a critical role in modulating the cellular localization of ICP0.
Thus, EGF signaling affects protein homeostasis by modulating the cellular anti-aggregation response.
Splicing variant ER isoforms also may be important in modulating the cellular response [ 38].
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Thus, it is believable that the size, shape, and the arrangement of nanotopographic features modulate the cellular response.
The ability to apply nanotechnology and materials engineering to modulate the cellular response has led to an abundance of possibilities.
The findings presented here could provide new means to modulate the cellular behaviors of HAPN and to guide the design of HAPN-based delivery and therapeutic systems.
However, a newly described class of bacterial polysaccharides has been characterized that have the ability to modulate the cellular immune system.
We propose new nanoparticle designs for infectious diseases, functionalized with ligands able to modulate the cellular immune response and concurrently deliver drug.
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modulating the resonant
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