Sentence examples for modulating the apoptotic process from inspiring English sources

Based on this initial report, the aim of the present study was to further characterise the pathways modulating the apoptotic process in activated human HSCs.

For example, the finding that loss of Cdk5 causes frank neurodegeneration with tissue atrophy even in the absence of any detectable effect on apoptosis raises the question of whether treatments aimed at modulating the apoptotic process will be effective in modifying disease course.

Coping with defensive systems of host organisms as growth environments, intracellular bacteria, such as Shigella and Legionella, are thought to have developed a variety of strategies for modulating the apoptotic process in host cells, especially during early stages of the life cycle [ 7].

Among the oncogenes, which may modulate the apoptotic process, Kit/Stem Cell Factor has a peculiar interest, since Kit is expressed in germ cells to some extent and Leydig cells, whereas SCF is expressed in Sertoli cells.

Another study suggested that melatonin may modulate the apoptotic process in the small intestine of mice exposed to 2.5 Gy gamma irradiation [ 60].

Macrophages can also promote trophoblast function by clearing apoptotic cells and secreting cytokines that regulate the apoptotic process [15].

In the apoptotic process, mitochondrial HK negatively modulates the cleaved form of Bid and may directly inhibit Bad, while Bid is inhibited by Akt.

Hence, the ROS NF-κB TGF-β1 signaling cascade is a possible mechanism by which alcohol induces the apoptotic pROS NF-κB TGF-β1s—a pROS NF-κB TGF-β1odulated by microglia.

It is tempting to speculate that the apoptotic process in some of these patients may be modulated or slowed by the individual's capacity to degrade misfolded insulin (by a process known as endoplasmic reticulum associated degradation).

DMPK−/− cardiomyocytes display increased levels of intracellular Ca2+, whereas the apoptotic process is affected when the levels of DMPK expression are modulated.

K balance is known to regulate the apoptotic cell shrinkage, a main event in the apoptotic process [ 12].