Sentence examples for modulating the actin from inspiring English sources

In the normal lung cells, Slit2 binds to Robo1 and activates downstream molecules, modulating the actin cytoskeleton and inhibiting cell migration.

These pathways include modulating the actin cytoskeleton, mediating signaling by Rho family GTPases and calmodulin, regulating E-cadherin and β-catenin function and organizing microtubules.

Hence, local concentrations of PIP2 may be used as a determinant for modulating the actin cytoskeleton and its related functions.

The Rho-like GTPase Rac1 is involved in migration and adhesion by modulating the actin cytoskeleton.

By modulating the actin cytoskeleton via Rho GTPases, YopE and ExoS inhibit bacterial uptake by macrophages (Black and Bliska, 2000; Deng and Barbieri, 2008).

Specifically, Rho GTPases, cAMP/PKA, and integrins were found to have a central role in modulating the actin cytoskeleton alterations during migration and have been shown to be closely regulated during epithelial to mesenchymal transition (EMT) processes [ 65, 66].

Centralspindlin, a complex composed of the subunits ZEN-4 and CYK-4, recruits and regulates proteins that modulate the actin cytoskeleton to promote cleavage furrow formation and progression during cytokinesis.

Enah, also known as MENA, modulates the actin cytoskeleton and cell signaling along with VASP.

It is tempting to speculate that NleL, NleG and Tir may work together to modulate the actin pedestal formation.

The ability of CRMP4 to modulate the actin cytoskeleton raises the possibility that CRMP4 plays an additional role in regulating actomyosin-based events during mitosis.

EphB-dependent regulation of dendritic filopodia motility and spine formation relies on forward signaling through guanine nucleotide exchange factors (GEFs) and other downstream molecules such as p21 activated kinase (PAK) that modulate the actin cytoskeleton [14], [17], [24], [25], [26].