Sentence examples for modulating the ability from inspiring English sources
Among the many efforts, one area of focus has been modulating the ability of antibodies to interact with the humoral and cellular components of the immune system through a process known as Fc engineering (Carter, 2006; Presta, 2008; Strohl, 2011).
Using this approach, we demonstrate that soft ECMs render cells maximally sensitive to changes in RhoA activity, and that by modulating the ability of cells to engage and contract soft ECMs, we can dynamically control cell spreading, migration, and matrix remodeling.
Previous work has shown that the calpain family of cysteine proteases can cleave talin between the head and rod domain, thereby modulating the ability of talin to activate integrins [5].
Changes in the yeast phenotype stimulated by FA may be due to the disruption of an existing protein interaction, by changing the stability of the protein (or), by modulating the ability of the protein to interact with other molecules, (or) by initiating a series of signal transduction pathways upon binding to a particular protein.
To examine further the effect of IFIT4 on modulating the ability of DCLCs to activate T-cell proliferation, an allogeneic MLR assay was conducted.
NF- κB is one of the major factors modulating the ability of cancer cells to resist apoptosis and to contribute to chemoresistance.
The apoA-I molecule adopts a two-domain tertiary structure and the properties of these domains modulate the ability to form HDL particles.
This led us to hypothesize that additional structural elements could modulate the ability of tyrosine residues to form covalent bonds.
We show that phosphorylation of FLRT1 in the cytoplasmic domain modulates the ability of FLRT to activate the MAPK pathway and induce neurite outgrowth.
More recently, mInscutable and Gαi3, two known AGS3-binding partners, have been shown to modulate the ability of AGS3 to distribute along the aggresomal pathway [21].
Several studies have suggested that phosphorylation of ADAM cytoplasmic tails may (directly or indirectly) modulate the ability of ADAMs to cleave physiological substrates [16], [17], [19], [33].
