Sentence examples for modulating sensitivity to from inspiring English sources

These results show that AAG is a key glycosylase for BER of NO-induced DNA damage and that XRCC1's role in modulating sensitivity to RONs is dependent upon the cellular level of AAG.

For example, it has been proposed that transcriptional responses play little, if any, role in modulating sensitivity to MMS [ 24] and other DNA-damaging agents [ 16].

Masahiro found continuous FGF stimulation to be necessary for the maintenance of VEGFR2 levels in mice modulating sensitivity to VEGF stimulation [ 38].

Yet, the de novo methyltransferases, DNMT3A and DNMT3B, may play a role in modulating sensitivity to X-rays in mESCs, as their absence seems to have a modest radioprotective effect.

As many of the metabolic outcomes of insulin are achieved through recruitment of PI3K and the subsequent rise in PIP3 levels, PTEN may have a critical role in modulating sensitivity to insulin-stimulated glucose uptake.

There is an emerging evidence supporting the role of miRNAs in modulating sensitivity to anticancer therapy, and miR-34a and miR-34b/c family in particular has been associated to prostate cancer survival and drug sensitivity.

Keratin intermediate filament expression in hES cells may modulate sensitivity to death receptor mediated apoptosis and stress.

Inducible expression of these genes can over-ride antiestrogen-induced growth arrest [13] and overexpression can modulate sensitivity to clinically-relevant antiestrogens in in vitro models [reviewed in Ref. 12].

Our study shows that the eEF-2 kinase-mediated autophagy plays a cytoprotective role in breast cancer cells treated with growth factor inhibitors, and inhibiting autophagic survival can modulate sensitivity to these therapeutic agents.

Honeybees, in particular, would be afforded a substantial fitness advantage: both the floral odor signals and food rewards' quality and quantity are highly variable, so the ability to modulate sensitivity to specific features in floral odors in accordance with reward quality could improve a foraging worker's efficiency for obtaining floral rewards.

However, still little is known about the regulatory mechanisms that modulate sensitivity to TNF-induced necroptosis.