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Hormone receptor (HR) status, one of the critical determinants of BC biology, had been suggested to be a factor modulating response to adjuvant chemotherapy in general and taxanes in particular.
Another Massachusetts General Hospital study showed that eight weeks of meditation shrunk the amygdala, the portion of the brain modulating response to fear and stress.
Moreover, albumin affects the pharmacokinetics of many drugs, thus, modulating response to treatment.
Experimental and clinical evidence suggest that hypoxia in solid tumours reduces their sensitivity to conventional treatment modalities modulating response to ionizing radiation or chemotherapeutic agents.
A number of studies have examined putative gene-environment interactions with childhood/adolescent MDD, where genes influence outcome by modulating response to environmental risk [ 40].
Although this study is the first to correlate MKP-1 levels to cetuximab resistance in CRC patients, the implication of other MKPs in modulating response to anti-EGFR therapy has previously been suggested.
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Salicylic acid is one of the important plant growth regulators which has a critical role in modulating responses to drought (Kang et al. 2014; Miura and Tada 2014).
In addition, we have found that the FGF targets MKP1 and DUSP5 are likely to contribute to the complex feedback loops involved in modulating responses to FGF signaling.
However, repopulating lymphocytes are critical for modulating responses to superinfection.
It plays an essential role in modulating responses to hypoxia by inducing or inhibiting multiple genes.
It was hypothesized that polymorphisms in these genes would influence DNA repair capacity, modulating responses to radiation and the risk of acute or chronic radiation-induced side effects.
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