Sentence examples for modulating p57 activity from inspiring English sources

We then analysed whether p57 phosphorylation by p38 was modulating p57 activity.

Morin promoted Nrf2 stability and its nuclear retention by possibly modulating PHLPP2 activity which subdues cellular Nrf2 responses by activating Fyn kinase.

To date, upstream signaling pathways governing mTORC1 activation have been studied extensively, while the mechanisms modulating mTORC2 activity remain largely elusive.

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1.

The spectrum of flavonoid effects spreads from inhibition of cyclin-dependent kinases (CDKs), which are critical for cell growth and division, to blocking angiogenesis and modulating MDR1 activity.

T229 (phosphorylated by PDK1) plays a key role in modulating S6K1 activity.

Additionally, we show that the CAM is capable of modulating P4 activity through the progesterone receptor.

These data indicate that direct phosphorylation of Nrf2 by MAPKs has limited contribution in modulating Nrf2 activity.

Our results support the idea that curtailing translation initiation by modulating eIF4A activity is a promising anti-cancer therapeutic approach that is well tolerated.

Again, we demonstrate, via mRNA expression and protein immunolocalization of the progesterone receptor, that the CAM is capable of modulating P4 activity.

We next wanted to determine if modulating Sirt1 activity or its expression would effect food intake and body weight of adult rats.