Sentence examples for modulating one of from inspiring English sources

Therefore, small molecules found to alter mammalian morphology may do so indirectly by modulating one of these pathways.

In the first case we examined the effect of an additional component modulating one of the two pathways.

IFN-γ is thus capable of modulating one of the most important processes driving tissue degeneration in arthritis.

Explicitly, we found that p35/Cdk5 plays an important role in their directed migration by phosphorylating ErbB4 and subsequently modulating one of the canonical ErbB4 signaling pathways, PI3-kinase/Akt.

This reduction in mRNA expression suggests that Hfq regulates motility and invasion at the transcription level, presumably by modulating one of the upstream regulators.

However, two distinct voltammetric features are not clearly resolved, regardless of the temperature, pH, or ionic strength (not shown), each of which could be a factor that would preferentially modulate one of the two cofactors' redox properties.

Here, we describe a novel gene from African swine fever virus (ASFV), I329L, which is able to modulate one of the most critical steps of the innate immune response by interfering with TLR3-stimulated activation.

Since KATP channels constitute key initiators of glucose-stimulated insulin secretion (GSIS), great effort has been devoted to the study of anti-diabetic drugs like the sulfonylureas, which modulate one of the two molecular components of the KATP channel (Bryan et al, 2005; Proks et al, 2002).

For example, 10Hz imaging speed was demonstrated by using a galvano-mirror to switch between UI and SI in case of GP SLI [ 24] or one can split the beam into + 1 and −1 order using a diffractive optical element and modulate one of the diffracted beam using high speed laser beam shutter in case of FP SLI.

Currently, the only examples of neutral, active, drug-like molecules able to modulate one of these critical pathways are the NAADP signalling probe 'Ned-19', that was identified by virtual screening, and very recently SAN2589 and SAN4825, identified by high-throughput screening, and specific to the cardiac cADPR signalling pathway.

The drug design process in modern times is highly dependent on Ehrlich's assumption (Kaufmann 2008), in which drugs work as "magic bullets" modulating one target of particular relevance to a disease.