Sentence examples for modulating gene regulation from inspiring English sources

Additional experiments of NF-YAs in Arabidopsis suggested their roles in modulating gene regulation through positive and negative mechanisms [ 58].

TEs can impact the gene content of a genome by inducing gene knockouts, modulating gene regulation or causing double-strand DNA breaks (DSBs) by TE excision.

In this study, our objective is to extend the analysis to inferring multiple modulators co-modulated gene regulation, using a correlation-based regression approach.

NO is well documented to modulate gene regulation at the transcriptional level in endothelial cells.

I provide a strategic view, illustrated by examples from human disease, that is relevant to variants occurring at any genomic location, whether in classical enhancer elements or other locations where there is the potential to modulate gene regulation.

Contraction or expansion of a codon repeat in a transcription factor has the potential to modulate gene regulation in a quantitative, rather than qualitative, manner [ 10, 30] and, therefore, result in a mutation of small effect [ 22].

Whereas our understanding of the molecular mechanisms by which TCDD modulates gene regulation is progressing, results reported on the neurotoxicity of AhR are not fully consistent with the current understanding.

Nevertheless, the above studies suggest a nuclear role of YAP/TAZ in modulating gene expression regulation and biological effects of the Wnt signaling pathway.

The secreted effectors are known to hijack host cellular machinery and thereby modulate gene regulation.

The 6-bp deletion in the 3′-UTR region of the TYMS gene (TYMS c.1494del6b) has been reported to modulate gene regulation at a post-transcriptional level through decreased mRNA stability (Mandola et al, 2004).

By modulating gene expression, the regulation of histone acetylation by histone acetyl transferase and histone deacetylase (HDAC) plays an important role in cell growth and differentiation.